A study on COVID-19 vaccine effectiveness has been published in JAMA Network Open after initially being withdrawn from the CDC's Morbidity and Mortality Weekly Report (MMWR).
The study, which indicates that COVID vaccines reduced the likelihood of severe illness, was originally scheduled for publication in March. Concerns were raised about its methodology by the acting CDC director, Jay Bhattacharya, after it had passed scientific review.
The study found that the vaccine lowered the odds of COVID-related emergency room visits by 50% and hospitalizations by 55%. It utilized a 'test-negative design' to compare vaccinated and unvaccinated individuals who sought medical care for respiratory symptoms. The publication has sparked discussions about the appropriateness of the methodology used.
The publication of this study may influence ongoing discussions about vaccine effectiveness and the methodologies used to assess it.
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